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Analysis of the Real-World Efficacy and Dose-Relatedness of Lenvatinib and PD-1 in the Treatment of Advanced/Recurrent Endometrial Cancer

Analysis of the Real-World Efficacy and Dose-Relatedness of Lenvatinib and PD-1 in the Treatment of Advanced/Recurrent Endometrial Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116943
Enrollment
Unknown
Registered
2026-01-16
Start date
2026-01-20
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced/Recurrent Endometrial Cancer

Interventions

Observation group:This study does not involve grouping.

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >=18 years. 2.Pathologically confirmed, discharge diagnosis, or outpatient diagnosis of endometrial cancer. 3.Received or are receiving treatment at the Gynecology Oncology Center of Peking Union Medical College Hospital. 4.Have received at least one cycle of lenvatinib treatment (either as monotherapy or in combination). 5.Have available baseline imaging data and at least one follow-up record for efficacy evaluation.

Exclusion criteria

Exclusion criteria: 1.Medical records are severely incomplete, making efficacy or safety evaluation impossible. 2.Concurrent diagnosis of other active malignant tumors.

Design outcomes

Primary

MeasureTime frame
Objective Response Rate, ORR;Progression-Free Survival, PFS;Disease Control Rate, DCR;Overall Survival, OS;

Secondary

MeasureTime frame
Lenvatinib Starting Dose;Lenvatinib Dose Adjustments;Adverse Event Severity;Adverse Event Incidence;

Countries

China

Contacts

Public ContactFan Rong

Peking Union Medical College Hospital

florafr@163.com+86 10 6915 5637

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026