Acute severe neurological diseases complicated by atelectasis and/or oxygenation impairment
Conditions
Interventions
Control group:Patients received a standardized supine position lung care protocol in the neuro-intensive care unit, which was designed to prevent and alleviate atel
Experimental group:During the study period, patients with neurological critical illness combined with atelectasis/hypoxemia who were decided by the clinical treatment te
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with neurological diseases who were diagnosed by a doctor as having severe brain injury based on clinical and CT or MRI findings during the study period, or with an Acute Physiology and Chronic Health Evaluation (APACHE II) score of >=12 at admission; 2.Invasive mechanical ventilation time >= 24h;
Exclusion criteria
Exclusion criteria: 1.Myocardial infarction occurred within the past 6 months, and there is severe decline or failure of organ functions such as heart, liver, lung, and kidney. 2.Suffering from severe bleeding tendency or coagulation dysfunction; 3.Suffering from severe neurological diseases, such as brain death, etc; 4.Musculoskeletal system diseases, such as fractures, muscle weakness, etc;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation Index;The incidence rate of pneumonia-related complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total length of hospital stay;Duration of mechanical ventilation; | — |
Countries
China
Contacts
Public ContactLi Zhimin; Tian Fei
Xuanwu Hospital Capital Medical University
Outcome results
None listed