Laparoscopic high ligation of the inguinal hernia sac was performed, and postoperative vomiting occurred
Conditions
Interventions
The afentanil group:Afentanil Hydrochloride Injection
Sponsors
Children's Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 3 Years
Inclusion criteria
Inclusion criteria: 1.Age 1 to 3 years old, gender not limited, ASA grade I to II; 2.Laparoscopic high ligation of the hernia sac will be performed at an elective date; 3.If the operation time is within 60 minutes, intravenous anesthesia is suitable during both the induction and maintenance of general anesthesia; 4.The legal guardian signs the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Cardiovascular system diseases: severe congenital heart disease (tetralogy of Fallot, etc.), severe arrhythmias (bradycardia/tachycardia requiring drug treatment, third-degree atrioventricular block), severe heart failure, etc; 2.Respiratory system diseases: Respiratory insufficiency, a history of bronchial spasm/asthma requiring treatment within one month before the screening period, acute upper respiratory tract infection within one week before the screening period with one of the following symptoms: obvious fever, wheezing or cough; 3.Gastrointestinal diseases: Gastrointestinal retention, active bleeding, and conditions that may lead to reflux and aspiration; 4.Central nervous system diseases: Patients with a history of craniocerebral injury, convulsions, epilepsy, intracranial hypertension, cerebral aneurysms, and cerebral vascular accidents; Or there is a known history of mental disorders (schizophrenia, mania, long-term use of psychotropic drugs, cognitive dysfunction, etc.); Those with known abnormal electroencephalograms; 5.Uncontrolled history of significant clinical diseases of the liver, kidneys, blood system, nervous system or metabolic system, etc; 6.Others: Developmental delay, obesity, diabetes, congenital conduction disorders, PONV history/family history, motion sickness; 7.Opioid allergy or contraindications to anesthesia; 8.Psychotropic drugs, antiemetic drugs or glucocorticoids were used 24 hours before the operation; 9.Pediatric populations that require special care or supervision by courts or social welfare institutions;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative vital signs;The incidence of postoperative irritability;The time for removing the tracheal tube;Eye-opening time;Pain Score (FLACC score); | — |
Countries
China
Contacts
Public ContactXu Ying
Children's Hospital of Chongqing Medical University
Outcome results
None listed