Depression with biological rhythm disorder
Conditions
Interventions
Experimental group:Provide weekly sessions of 45-minute IPSRT treatment for a duration of 12 weeks.
Control group:Provide weekly health education on sleep hygiene for 20 minutes, along with guidance on sleep behaviors.
Sponsors
The First People's Hospital of Hangzhou
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18 - 65 years old; 2. Meets the clinical diagnostic criteria for major depressive episode as per DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition); 3. HDRS-17 (Hamilton Depression Scale 17 items) > 17 points; 4. Total score of Pittsburgh Sleep Quality Index (PSQI) >= 7 points; 5. Neuro-psychiatric biological rhythm assessment interview >= 29 points; 6. No medication treatment received; 7. All patients and their families gave informed consent for this study;
Exclusion criteria
Exclusion criteria: 1. Individuals with other DSM-5 spectrum disorders; 2. Mental disorders caused by substance abuse (alcohol, drugs, etc.); 3. Those with severe physical illnesses; 4. Those who have received drug treatment within the last 3 months before enrollment (such as antidepressants, antipsychotic drugs, sedative-hypnotic drugs, etc.); 5. Those who currently have serious suicidal thoughts or behaviors (MADRS (Montgomery-Asberg Depression Scale) item 10 on suicidal ideation >= 4 points), or those with severe agitation; 6. Those who have received electroconvulsive therapy within the last month; 7. Those who have participated in other clinical trials of investigational drugs within the past 60 days;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep quality;Depressive symptoms;Sleep phase monitoring;Biological rhythm; | — |
Countries
China
Contacts
Public ContactChunxiao Dai
The First People's Hospital of Hangzhou
Outcome results
None listed