Sleep disorder
Conditions
Interventions
Remimazolam group:Total intravenous anesthesia with remimazolam
Sponsors
The Fourth Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily sign the informed consent form. 2. Age 60-75 years, BMI: 18-28 kg/m². 3. Patients with preoperative pathological diagnosis of malignant gastrointestinal tumors. 4. ASA classification: I-III. 5. Elective surgery under endotracheal intubation general anesthesia. 6. Expected surgical duration exceeding 2 hours, estimated postoperative hospital stay exceeding 5 days.
Exclusion criteria
Exclusion criteria: 1. The patient refuses to participate in this study. 2. Preoperative diagnosis of severe respiratory, cardiovascular, renal, or hepatic dysfunction. 3. Preoperative Pittsburgh Sleep Quality Index (PSQI) score >7. 4. History of schizophrenia, epilepsy, Parkinson's disease, myasthenia gravis, or other psychiatric disorders. 5. Cognitive impairment or inability to communicate due to severe visual, auditory, or language deficits. 6. Allergy or contraindication to propofol or benzodiazepines.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of sleep disorders on the first day after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The total sleep duration on the first day after surgery;The sleep latency on the first day after surgery;The number of awakenings after falling asleep on the first day after surgery;The duration of light sleep stage;The duration of deep sleep stage;The duration of rapid eye movement (REM) sleep;Apnea-Hypopnea Index;Oxygen Desaturation Index; | — |
Countries
China
Contacts
Public ContactChao Li
The Fourth Hospital of Hebei Medical University
Outcome results
None listed