Dry Eye Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged between 18 and 45 years (inclusive); 2.Best-corrected visual acuity in both eyes >= 0.8 (4.9); refractive errors requiring long-term use of glasses; 3.Participants voluntarily take part in the study, provide written informed consent, and are able to comply with the required ophthalmic examinations and questionnaire assessments;
Exclusion criteria
Exclusion criteria: 1.A history of ocular trauma or any ocular surgery, including refractive procedures; 2.Presence of active ocular disease (e.g., ocular inflammation, allergy), binocular vision dysfunction, eyelid abnormalities, or any other ocular conditions that may affect the study outcomes; 3.Current use of any topical ophthalmic medications other than artificial tears; 4.Long-term contact lens wear (average daily wearing time >= 5 hours over the past 3 months); Wore soft contact lenses within 1 week prior to screening, or wore rigid contact lenses within 1 month prior to screening; 5.Any systemic diseases, systemic medication use, or other factors that, in the investigator’s judgment, may make the participant unsuitable for this study; 6.Participants who are concurrently enrolled in any other clinical trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fluorescein tear breakup time (FTBUT) and corneal fluorescein staining score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraocular pressure (IOP);Lipid Layer Thickness (LLT);Lower tear meniscus height (LTMH);Non-invasive tear breakup time (NITBUT) and conjunctival hyperemia score;SANDE Questionnaire;Continuous Functional Visual Acuity (FVA) test;CVS-Q score; | — |
Countries
China
Contacts
Eye Hospital, Wenzhou Medical University