Major depressive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age range: 14 - 65 years old; 2. Baseline HAMD-17 score >= 7 points; 3. First onset or recurrence without medication use (> 3 months);
Exclusion criteria
Exclusion criteria: 1. Patients with mental disorders such as bipolar disorder and schizophrenia; 2. Patients with refractory depression (those who have failed to respond to =2 kinds of adequate antidepressant medications in the past); 3. Patients with severe physical diseases; 4. Patients with substance abuse disorders;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-17-item scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolomics indicators;Drug genomics indicators;Proteomics indicators; | — |
Countries
China
Contacts
Ningbo University Affiliated Kangning Hospital