Acute Ischemic Stroke
Conditions
Interventions
Group with poor prognosis:NA
Group with good prognosis:NA
Sponsors
Yuebei People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old, gender is not limited; 2. Receive EVT treatment (such as mechanical thrombectomy, stent implantation, etc.); 3. Complete blood count and biochemical metabolic index tests (which can calculate biomarkers) within 24 hours before surgery; 4. Have complete pre - operative/post - operative imaging data (pre - operative NCCT/CTA, immediate post - operative NCCT, post - operative 24 - 48h CT/MRI); 5. The follow-up data of mRS scores at 30/90 days after surgery are complete;
Exclusion criteria
Exclusion criteria: 1. Merge hemorrhagic stroke (such as cerebral hemorrhage, subarachnoid hemorrhage), brain tumors, intracranial infections, brain trauma and other intracranial lesions; 2. Severe liver and kidney failure: Child-Pugh class C, or serum creatinine > 300 µmol/L, or alanine aminotransferase (ALT) > 3 times the upper limit of normal; 3. The core indicators required for biomarker calculation are missing (such as neutrophil count, triglyceride), and cannot be supplemented through the original laboratory reports or medical records. 4. Imaging data is incomplete or of poor quality: for example, the preoperative CTA does not clearly show the responsible blood vessel, and the postoperative MRI has severe artifacts that make it impossible to measure the infarct volume; 5. The postoperative follow - up time is less than 90 days, or the follow - up data is incomplete (for example, only 30 - day follow - up is completed, and the 90 - day follow - up is lost to follow - up); 6. Combine terminal stage of malignant tumors (expected survival period 10mg/d); 7. Clinical data is severely lacking (e.g., no surgical records, no baseline NIHSS scores).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified mRS score at 90 days after operation (mRS = 3 indicates a poor functional outcome); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complicationsPostoperative complications (symptomatic intracranial hemorrhage, pulmonary infection, gastrointestinal bleeding, etc.); | — |
Countries
China
Contacts
Public ContactXiang Liu
Yuebei People’s Hospital
Outcome results
None listed