Patients confirmed as HIV-positive with reference to the Chinese Guidelines for HIV/AIDS Diagnosis and Treatment (2024 Edition) and verified by the Center for Disease Control and Prevention
Conditions
Interventions
Patient group planned for conversion to the AINOMITI regimen:None
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Voluntarily signed informed consent form; 2. Age >= 18 years, gender unrestricted; 3. Patients confirmed as HIV-infected according to the "Chinese Guidelines for HIV/AIDS Diagnosis and Treatment (2024 Edition)" by the Center for Disease Control and Prevention; 4. LDL-C >= 3.0 mmol/L (according to the European EACS Guidelines 12.0 recommendation that the treatment target for HIV-infected individuals is LDL-C < 3.0 mmol/L), i.e., patients requiring lipid intervention; 5. Patients on ART for more than one year with virologic suppression and a recent HIV-1 RNA < 40 copies/mL test result within the past six months; 6. Patients who, upon physician’s order, require conversion to the AINOMITI regimen based on clinical condition.
Exclusion criteria
Exclusion criteria: 1.History of NNRTI resistance (except for K103N, Y181C, L100I, or G190A mutations); 2.Frequent ART regimen changes (>=2 modifications in the past year); 3.Current use of lipid-lowering medications; 4.Deemed ineligible by investigators based on clinical judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Routine Laboratory Examinations and Biochemical Parameters;Immunological and Virological Parameters;Examination Parameters;Metabolic Parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic Data;Medical History;Framingham score;Physical Examination Data; | — |
Countries
China
Contacts
Public ContactPeng Jie
Southern Medical University Southern Hospital
Outcome results
None listed