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Infiltration concentration of bupivacaine in liposome ultrasound-guided peripheral nerve block: a sequential dose-allocation study

Infiltration concentration of bupivacaine in liposome ultrasound-guided peripheral nerve block: a sequential dose-allocation study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116783
Enrollment
Unknown
Registered
2026-01-14
Start date
2025-07-02
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper limb fracture

Interventions

Observation group:None

Sponsors

Xiamen Humanity Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The upper limb fractures were diagnosed by imaging examination, including but not limited to humeral fractures, ulnar-radial fractures, etc.Patients with upper limb fractures who intend to undergo surgical treatment; the time from post-fracture to enrollment is within the specified range (e.g. within 72 hours);The American Society of Anesthesiologists (ASA) physical condition is graded I-III, indicating that the patient's overall health is relatively stable and can tolerate anesthesia and surgery;Preoperative evaluation of normal nerve function, no history of nerve injury;Patients voluntarily participated in this study and signed informed consent forms.It is expected that the postoperative hospitalization observation time can meet the follow-up requirements of the study.

Exclusion criteria

Exclusion criteria: Allergic to bupivacaine or liposomal components;There is severe liver and kidney dysfunction, which may affect drug metabolism and excretion;Suffering from coagulation dysfunction or receiving anticoagulation therapy, increasing the risk of bleeding.A history of neurological disorders, such as neurodegenerative disorders and epilepsy, may affect the assessment of pain perception and response.Have recently used other medications that may affect nerve function or pain perception, such as within one month.Suffering from mental illness or cognitive impairment, unable to cooperate with research or accurately describe pain feelings.Women who are pregnant or breastfeeding.There are systemic infections or local infections that have not been effectively controlled.

Design outcomes

Primary

MeasureTime frame
NRS score;Muscle strength score;

Secondary

MeasureTime frame
Adverse reaction;

Countries

China

Contacts

Public ContactJin Lin

Xiamen Humanity Hospital

116238174@qq.com+86 138 6016 4980

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026