Pancreatic cancer, bile duct cancer, ampullary cancer, benign/ borderline pancreatic tumors
Conditions
Interventions
Extended Output Loop Group:Braun anastomosis with an extended output loop (30–40 cm) in pancreaticoduodenectomy
Standard Output Loop Group:Braun anastomosis with a standard-length output loop (10–15 cm) in pancreaticoduodenectomy
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Obtain informed consent signed by the patient or their legal representative, indicating willingness to participate in the study; 2. Compliance with the study protocol and follow-up procedures; 3. Patients aged between 18 and 80 years, regardless of gender; 4. No contraindications to surgical procedures, able to tolerate radical surgery, with an ECOG performance status of 0–1 and an ASA score of <=2; 5. Preoperative diagnosis of pancreatic cancer, bile duct cancer, ampullary cancer, or benign/borderline pancreatic tumors based on clinical symptoms, imaging studies, tumor markers, and other ancillary examinations, and recommended for PD after multidisciplinary consultation.
Exclusion criteria
Exclusion criteria: 1. Presence of other malignancies within the past year: patients with brain, lung, bone metastasis or peritoneal lymph node metastasis. 2. Severe dysfunction of the heart, lungs, liver, or kidneys. 3. Infection with HCV, HIV, or syphilis. 4. Pregnant or breastfeeding women. 5. Preoperative treatment with chemotherapy, immunotherapy, or targeted therapy. 6. Palliative surgery for the tumor. 7. Patient refusal to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delayed gastric emptying;Pancreatic fistula; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bile leakage ;Intra-abdominal infection;Bowel obstruction;Portal vein thrombosis; | — |
Countries
China
Contacts
Public ContactZhang Wen
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed