Determination of the Median Effective Dose of Iliopsoas Plane Block in Elderly Patients With Hip Fracture Using the Up-and-Down Method

Determination of the Median Effective Dose (ED50) of 0.375% Ropivacaine for Ultrasound-Guided Iliopsoas Plane Block in Elderly Patients With Hip Fracture: An Up-and-Down Sequential Study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600116752

Enrollment

Unknown

Registered

2026-01-14

Start date

2026-01-14

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip fracture in elderly patients

Interventions

IPB group:Ultrasound-guided iliopsoas plane block using 0.375% ropivacaine. The initial volume is 10 ml, with a step size of 1 ml according to the up-and-down sequential method. Analgesic efficacy is

Eligibility

Sex/Gender

All

Age

65 Years to 120 Years

Inclusion criteria

Inclusion criteria: 1. Age >=65 years, scheduled for surgery due to unilateral hip fracture; 2. American Society of Anesthesiologists (ASA) physical status I–III; 3. Visual analogue scale (VAS) score >=5 during movement before block; 4. Ability to understand the study protocol and provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe cardiovascular disease; 2. Psychiatric or neurological disorders impairing cooperation; 3. Coagulopathy or infection at the puncture site; 4. Known allergy to local anesthetics.

Design outcomes

Primary

Measure	Time frame
Analgesic efficacy of iliopsoas plane block;	—

Secondary

Measure	Time frame
Adverse reactions ( puncture site hematoma, local anesthetic poisoning, nerve injury );	—

Countries

China

Contacts

Public ContactJianhong Peng

Foshan Hospital of Traditional Chinese Medicine

295336187@qq.com+86 136 2010 4951

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026