Cardiac Arrest
Conditions
Interventions
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years 2.Cardiac arrest (out-of-hospital or in-hospital), confirmed by documentation 3.Return of Spontaneous Circulation (ROSC) = 20 minutes (defined as sustained ROSC) 4.Informed consent obtained: The patient’s authorized representative provides consent within 24 hours after ROSC (if immediate signing is not possible, the deferred consent process approved by the center’s ethics committee will be followed)
Exclusion criteria
Exclusion criteria: 1.Pregnancy 2. Cardiac arrest caused by organic diseases of the central nervous system (e.g., cerebral hemorrhage, ischemic stroke, brain herniation, etc.) 3. Patients with traumatic brain injury; history of severe neurological diseases (e.g., dementia, sequelae of stroke) 4.Terminal illnesses, such as end-stage malignant tumors 5. Early treatment limitation: Planned withdrawal of life support within 24 hours of admission for reasons unrelated to neurological prognosis (e.g., refractory multiple organ failure, indicators of treatment futility) 6.Inability to perform timely blood sampling/follow-up 7.Conditions that may severely interfere with the interpretation of biomarkers (e.g., active infectious/inflammatory central nervous system disease at admission, significant hemolysis rendering samples unusable)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebral Performance Category,CPC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cerebral Performance Category,CPC;30-day mortality rate; | — |
Countries
China
Contacts
Public ContactHuadong Zhu
Peking Union Medical College Hospital
Outcome results
None listed