Pediatric Preoperative Separation Anxiety
Conditions
Interventions
Remimazolam Group:Before entering the operating room, an intravenous access is established. Under the accompaniment of a parent, remimazolam is administered intravenously at a dose of 0.3 mg/kg, with
Esketamine Group:Before entering the operating room, an intravenous access is established. Under the accompaniment of a parent, esketamine is administered intravenously at a dose of 0.5 mg/kg, with co
Dexmedetomidine Group:Before entering the operating room, an intravenous access is established. Under the accompaniment of a parent, dexmedetomidine is administered intravenously at a dose of 1 µg/kg,
Sponsors
Hubei Maternal and Child Health Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 5 Years
Inclusion criteria
Inclusion criteria: Children aged 2 to 5 years old with an American Society of Anesthesiologists (ASA) physical status of Class I, who are scheduled for adenotonsillectomy under general anesthesia, will be included.
Exclusion criteria
Exclusion criteria: Abnormal lung function and respiratory system function, airway obstruction or deformity, history of mental illness, electrocardiogram indicating bradycardia, history of cardiac disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success rate;Onset time of sedation;Parent-Child Separation Anxiety Score (PASA Score);Heart rate, blood pressure, respiratory rate, and pulse oximetry saturation at 0, 3, 5, and 10 minutes after administration of the sedative.;Recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mask Acceptance Score (MAS);ncidence of adverse reactions during intravenous bolus administration of sedative drugs and anesthesia induction; | — |
Countries
China
Contacts
Public ContactJin Shuangfen
Hubei Maternal and Child Health Hospital
Outcome results
None listed