Obesity
Conditions
Interventions
Experimental group:Wearing a u nasal aspirator containing a mixture of 2-oxovaluric acid liquid solvent and hydrogel, three times a day, each time before three meals, lasting for 12 weeks, and each ti
Sponsors
Shandong First Medical University Affiliated Central Hospital (Jinan Central Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Individuals aged 18 to 65 years with normal olfactory function; 2. BMI >= 28 kg/m^2, or 24 kg/m^2<= BMI < 28 kg/m^2 with at least one weight-related comorbidity (such as hyperglycemia, hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease); 3. Good adherence to the study protocol; 4. The participant or their close relatives can fully understand the informed consent form, agree to participate in the study, and sign the consent form.
Exclusion criteria
Exclusion criteria: 1. Have participated in other clinical trials in the past three months; 2. Have used medications that affect body weight within three months prior to screening, including glucagon-like peptide-1 agonists, corticosteroids, metformin, sodium-glucose co-transporter 2 inhibitors, sibutramine hydrochloride, creatine, etc.; 3. Subjects who are allergic to the components of the nasal clip or have an allergic constitution; 4. Subjects with any other factors that may affect the efficacy or safety evaluation of this study, making them unsuitable for participation; 5. Individuals with olfactory dysfunction with a baseline TDI Score <30.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weight; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body Composition Analysis; | — |
Countries
China
Contacts
Public ContactYongfeng Song
Shandong First Medical University Affiliated Central Hospital (Jinan Central Hospital)
Outcome results
None listed