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Study on the mechanism of inflammatory endotype in odontogenic sinusitis

Study on the mechanism of inflammatory endotype in odontogenic sinusitis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116708
Enrollment
Unknown
Registered
2026-01-14
Start date
2026-01-23
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Odontogenic sinusitis

Interventions

Observation group:N/A

Sponsors

Beijing Tongren Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.According to the diagnostic criteria of the 2020 European Position Paper on Rhinosinusitis and nasal Polyps, the patients who met the above disease codes were further divided into the odontogenic maxillary sinusitis (OMS) group and the non-OMS group, and the sinus healthy control group was set up. 2.The age of all subjects ranged from 18 to 70 years.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with severe cardiopulmonary dysfunction, systemic diseases or coagulopathy.

Design outcomes

Primary

MeasureTime frame
Maxillary sinus mucosal thickness;Distance from the tooth root to the maxillary sinus floor.;Area of the sinus floor bony defect;Inflammatory cell density;Density of IL-17A, IL-5, and IFN-?-positive cells;

Secondary

MeasureTime frame
Gender;Age;Smoking history;Oroantral Communication;RNA expression of Th cells from maxillary sinus mucosa;

Countries

China

Contacts

Public ContactJiang Lin

Beijing Tongren Hospital, Capital Medical University

kelvinperio@163.com+86 136 9911 1207

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026