Cerebral hemorrhage
Conditions
Interventions
Sponsors
Huashan Hospital affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Cerebral hemorrhage Part I cohort: Age > 18 years; Parenchymal hemorrhage (spontaneous or traumatic) confirmed by head CT; The onset time was within 6 hours; Patients were admitted to the ICU ward of our hospital. The temporal window had good sound transmission (the contralateral skull and midline structures could be shown). Patients or their families provided written informed consent. 2. Cerebral hemorrhage part 2 cohort: age above 18 years old; Spontaneous intracerebral hemorrhage confirmed by head CT; The admission time was within 2 hours; The temporal window had good sound transmission. Patients or their families provided written informed consent. 3. Parkinson's cohort: PD patients who were first admitted to the hospital were selected; Be over 60 years of age; Patients were assessed by the Movement Disorders Society Revised Parkinson's Disease Rating Scale (MDS-UPDRS). Written informed consent was obtained.
Exclusion criteria
Exclusion criteria: 1. Cerebral hemorrhage Part I cohort: Craniotomy for hematoma evacuation has been performed; pregnant women; presence of surgical wounds or dressings in the temporal region impairing probe placement; severe cases expected to die within 24 hours of admission. 2. Cerebral hemorrhage Part II cohort: Emergency surgical indication present at admission. 3. Parkinson’s cohort: Presence of severe central nervous system disorders such as psychiatric illness, cerebrovascular disease, or dementia; coexistence of other disorders with parkinsonian symptoms such as essential tremor; presence of Parkinson’s plus syndromes; history of traumatic brain injury or neurosurgery; intracranial lesions identified on CT or MRI with corresponding neurological symptoms; history of carbon monoxide or other chemical/drug poisoning; other neurodegenerative diseases such as multiple system atrophy or progressive supranuclear palsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hematoma size;Midline of brain;Substantia nigra area; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraventricular hemorrhage;Width of the third ventricle;Hematoma volume;Compression of peribrainstem cisterns;Cerebral blood flow parameters;Substantia nigra/midbrain area;MDS-UPDRS scale score; | — |
Countries
China
Contacts
Public ContactDing Hong, Li Yiming
Huashan Hospital affiliated to Fudan University
Outcome results
None listed