pain
Conditions
Interventions
Patients receiving nalbuphine:Patients received intravenous continuous infusion of nalbuphine hydrochloride injection (1 mL: 10 mg), with a loading dose of 80 µg/kg followed by a maintenance dose of 0
Sponsors
Guangdong Second Provincial General Hospital (Guangdong Provincial Emergency Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Post-abdominal surgery; 2.Aged 18-80 years old; 3.Gender is not limited;
Exclusion criteria
Exclusion criteria: 1.Allergic to nalbuphine or other ingredients of this product; 2.Pregnant and lying-in women; 3.Mental disorders or taking antipsychotic drugs; 4.Long-term or past use of drugs; 5.Allergic to opioids or having used opioids within one month; 6.Suffering from significant respiratory depression-related diseases; 7.Intestinal obstruction; 8.Transferred in after gallbladder or biliary tract surgery; 9.Participated in a drug clinical trial within three months; 10.Other situations that doctors consider unsuitable for participating in clinical trials;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain control achieved: CPOT <= 2 or NRS <= 2 within 24 hours after first dose.Pain control achieved: CPOT <= 2 or NRS <= 2 within 24 hours after first dose.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation;Length of ICU stay;Cost of analgesics; | — |
Countries
China
Contacts
Public ContactYunfeng Song
Guangdong Second Provincial General Hospital (Guangdong Provincial Emergency Hospital)
Outcome results
None listed