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Impact of Different Peri-Implantation estradoil levels on Embryo Implantation and Pregnancy Maintenance: A Multicenter Study

Impact of Different Peri-Implantation estradoil levels on Embryo Implantation and Pregnancy Maintenance: A Multicenter Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116682
Enrollment
Unknown
Registered
2026-01-13
Start date
2026-01-20
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Study 1:N/A
Study 2:N/A

Sponsors

The First Affiliated Hospital of Guilin Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 43 Years

Inclusion criteria

Inclusion criteria: Study 1 1. Long stimulation protocol or antagonist protocol; 2. Meet the criteria for fresh cycle transfer; 3. Age 20-43 years. Study 2 1. Age 20-43 years; 2. Long stimulation protocol or antagonist protocol suitable for fresh embryo transfer; 3. Meet the criteria for frozen-thawed embryo transfer, including natural ovulation cycles and artificial cycles (oral estrogen and progesterone).

Exclusion criteria

Exclusion criteria: Study 1 1. Use of estrogen drugs during ovulation induction or after egg retrieval. 2. Those with uterine anatomical abnormalities, endometrial lesions, or hydrosalpinx; 3. Autoimmune diseases, thrombotic tendency; 4. Ovarian hyperstimulation syndrome. Study 2 1. Use of estrogen before pregnancy testing in all protocols except HRT cycles; 2. Exclude autoimmune diseases and thrombotic tendency. 3. Those with uterine anatomical abnormalities, endometrial lesions, or hydrosalpinx.

Design outcomes

Primary

MeasureTime frame
Estrogen levels;

Countries

China

Contacts

Public ContactHuang Pinxiu

The First Affiliated Hospital of Guilin Medical University/Guilin Medical University Affiliated Hospital

huangpinxiu@163.com+86 183 7728 5169

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026