Emergence Agitation
Conditions
Interventions
Experimental Group (Oxycodone Group):Oxycodone hydrochloride injection (0.1 mg/kg) was administered intravenously and slowly 30 minutes before the end of surgery.
Control Group (Sufentanil Group):An equivalent analgesic dose (oxycodone:sufentanil potency ratio = 1000:1) of matched placebo-appearing sufentanil citrate injection (0.1 µg/kg) was administered intra
Sponsors
The First Affiliated Hospital of Chengdu Medical College
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients scheduled for thoracoscopic-assisted or open pulmonary surgery at The First Affiliated Hospital of Chengdu Medical College; (2) Age >= 65 years; (3) American Society of Anesthesiologists (ASA) physical status classification II–III; (4) All participants provided signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Preoperative long-term use of opioids (>1 month) or history of drug abuse; 2. Severe hepatic or renal dysfunction (Child-Pugh C class, eGFR = 35 kg/m²); 11. History of difficult airway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Coughing score during extubation period;extubation time;Respiratory function indicators: PaO2, PaCO2, respiratory rate; | — |
Countries
China
Contacts
Public ContactTu Tao
The First Affiliated Hospital of Chengdu Medical College,Department of Anesthesiology
Outcome results
None listed