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The effect of oxycodone on ventricular function in children with congenital heart disease

The effect of oxycodone on ventricular function in children with congenital heart disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116643
Enrollment
Unknown
Registered
2026-01-13
Start date
2026-01-20
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Heart Disease?

Interventions

S group: Sufentanil group :For anesthetic induction, the S group received sufentanil at 1 µg/kg, while the O group received oxycodone at 1 mg/kg. All other drugs were administered routinely using the
O group: Oxycodone group:For anesthetic induction, the O group received oxycodone at 1 mg/kg. All other drugs were administered routinely using the same dosages and sequence.

Sponsors

Shanghai children’ s Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 6 Years

Inclusion criteria

Inclusion criteria: Aged 3 months to 6 years; Any gender; Diagnosed with congenital heart disease and scheduled for elective corrective surgery; ASA class II-IV; Informed consent provided by guardian.

Exclusion criteria

Exclusion criteria: Emergency surgery; Pre-existing severe organic dysfunction; Preoperative use of vasoactive drugs; Legal guardian declined to participate in the study.

Design outcomes

Primary

MeasureTime frame
Global Longitudinal Strain;Global Constructive Work;Left Ventricular Ejection Fraction;Stroke Volume Index;Cardiac index;Global Work Index;Global Wasted Work;Global Work Efficiency;

Secondary

MeasureTime frame
Interleukin-6;Tumor Necrosis Factor-alpha;

Countries

China

Contacts

Public ContactJi Wei

Shanghai children’ s Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine/Shanghai Children's Medical Center

jiwei719@163.com+86 156 1898 3719

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026