Study on the mechanism of SKAP1 promoting neutrophil extracellular traps through NFATc1/CXCL8 axis and participating in liver cancer immune escape

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2600116627

Enrollment

Unknown

Registered

2026-01-13

Start date

2026-01-15

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

Hepatocellular carcinoma tissues:NA

adjacent normal liver tissues:NA

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Postoperative pathological diagnosis of hepatocellular carcinoma (HCC); 2. The tumor and paired adjacent tissues are intact; 3. Complete clinical data; 4. Not receiving radiotherapy or chemotherapy before surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with other malignant tumors and missing data were excluded. 2. Those whose pathological diagnosis does not meet the inclusion criteria.

Design outcomes

Primary

Measure	Time frame
Protein and gene expression levels of SKAP1, NFATc1, and CXCL8;	—

Countries

China

Contacts

Public ContactYu Qingjiang

The First Hospital of Jiaxing

41995337@qq.com+86 573 8359 9088

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026