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Research on Symptom Interaction Mechanisms and Intelligent Precision Intervention Models in Multiple Myeloma Chemotherapy Patients from a Dynamic Network Perspective

Research on Symptom Interaction Mechanisms and Intelligent Precision Intervention Models in Multiple Myeloma Chemotherapy Patients from a Dynamic Network Perspective

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116622
Enrollment
Unknown
Registered
2026-01-13
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Myeloma

Interventions

Visual Group:Patients in this group will receive unimodal visual sensory stimulation by immersively experiencing a virtual forest scene through the VR headset.
Auditory Group:Patients in this group will receive unimodal auditory sensory stimulation by listening to the complete natural soundscape via the built-in headphones of the VR headset.
Olfactory Group:Patients in this group will receive unimodal olfactory sensory stimulation by receiving standardized forest scent stimuli through the aroma clip.
Multimodal Group:Patients in this group will receive combined stimulation across the visual, auditory, and olfactory sensory channels simultaneously.
Control Group:Patients in this group will sit quietly and rest in a comfortable position for 15 minutes in a quiet therapy room without using any sensory intervention equipment. Adhering to ethical pr

Sponsors

Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of the Chinese Guidelines for the Diagnosis and Management of Multiple Myeloma (2024 Revision); 2.Age >= 18 and =3 and < 7, indicating mild to moderate pain; 5. Provide informed consent and voluntarily participate in the study; 6. Possess normal hearing, speaking, reading, and writing abilities.

Exclusion criteria

Exclusion criteria: 1.Have impaired consciousness or a history of mental disorders; 2.Have comorbid other malignancies or severe concurrent illnesses (e.g., cardiac failure, major trauma, etc.); 3.Have severe visual, auditory, or olfactory dysfunction; 4.Have a history of motion sickness, epilepsy, encephalitis, or other central nervous system diseases; 5. Are concurrently participating in other clinical trials that may interfere with the results of this study.

Design outcomes

Primary

MeasureTime frame
Pain Numerical Rating Scale;Brief Pain Inventory;Resting-state electroencephalogram;

Secondary

MeasureTime frame
State-trait Anxiety Inventory, S-A;

Countries

China

Contacts

Public ContactChen Jing

Zhengzhou University

chj@zzu.edu.cn+86 135 2650 3365

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026