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The effect of high flow nasal oxygen inhalation on intraoperative oxygenation in elderly patients undergoing vitrectomy under basic anesthesia: a multicenter randomized controlled study

The effect of high flow nasal oxygen inhalation on intraoperative oxygenation in elderly patients undergoing vitrectomy under basic anesthesia: a multicenter randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116609
Enrollment
Unknown
Registered
2026-01-13
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ophthalmic Anesthesia

Interventions

HFNC group:Administer high-flow nasal oxygen at a concentration of 40%, starting at a flow rate of 10 L/min, and increase the flow by 10 L/min every 3 minutes until reaching 30 L/min.
Conventional Nasal Cannula Group:Administer oxygen via conventional nasal cannula at a flow rate of 2 L/min, with an oxygen concentration of 100%.

Sponsors

The First Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The patient underwent elective vitrectomy under basal anesthesia at our hospital. 2. The patient's age is no less than 65 years old. 3. The oxygen inhalation time is not less than 1 hour.

Exclusion criteria

Exclusion criteria: 1. Patients with impaired consciousness who are unable to cooperate. 2. Patients with severe organ dysfunction. 3. Severe type I respiratory failure. 4. Moderate to severe respiratory acidosis with hypercapnia (pH < 7.30). 5. Patients with concurrent mental disorders or other relevant diseases. 6. Patients or their family members refuse enrollment in the study.

Design outcomes

Primary

MeasureTime frame
Oxygenation Index;

Secondary

MeasureTime frame
Blood pressure;heart rate;Fingertip oxygen saturation;Patient Satisfaction Score;Anesthesiologist and Surgeon Satisfaction Score;

Countries

China

Contacts

Public ContactWang Kun

The First Affiliated Hospital of Harbin Medical University

hydwangkun@sina.com+86 139 3601 3651

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026