intracranial vertebral artery stenosis
Conditions
Interventions
Case group:None
Sponsors
People's Hospital of Leshan
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1.Age >=18 years, male or female; 2.Clinical and angiographic indication for intracranial vertebral artery stenosis (V4) >=50% with transient ischemic attack (TIA) or posterior circulation ischemia:; 3.Written informed consent.
Exclusion criteria
Exclusion criteria: 1.Known contraindication to DAPT treatment or endovascular intervention (i.e. major coagulation abnormalities, uncontrolled severe infections, severe systemic illnesses, uncontrolled hypertenshion); 2.Complicated with aneurysm, that cannot be treated earlier or at the same time or contraindication to surgery; 3. Gastrointestinal Diseases with active bleeding; 4.Myocardial infarction or major massive cerebral infarcts within 2 weeks; 5.Complicated with atrial fibrillation or history of anticoagulant; 6.Known hypersensitivity or contraindication to heparin, sirolimous, anaesthetic and contrast dye; 7.Bedridden or with other severe diseases; 8.Life expectancy less than 12 month; 9.According to the judgement of the investigator, other situations that are not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Any TIA, Stroke or all-caused Death Within 30 Days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cerebrovascular event;mRS ranking;Target lesion revascularization;NIH Stroke Scale;degree of stenosis;In-stent Restenosis or stent fracture;size, Calcification, fibrosis of Plaque; | — |
Countries
China
Contacts
Public ContactBo Lei
People's Hospital of Leshan
Outcome results
None listed