COMISA (Comorbid Insomnia and Obstructive Sleep Apnea)
Conditions
Interventions
Sponsors
The Second Affiliated Hospital Of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Healthy control group: (1) PSG monitoring: AHI = 5 events/hour); (2) No symptoms meeting the diagnostic criteria for insomnia disorder according to ICSD-3; (3) No prior treatment with CPAP or other OSA therapies; (4) No use of sedative-hypnotic medications in the past 3 months. Simple insomnia group: (1) Meets the diagnostic criteria for insomnia disorder according to ICSD-3 or DSM-5; (2) PSG results: AHI < 5 events/hour (excluding OSA); (3) No other sleep disorders (such as restless legs syndrome, circadian rhythm sleep-wake disorders, etc.); (4) No regular use of hypnotic medications or cognitive behavioral therapy. COMISA group: Meets the diagnostic criteria for both OSA and insomnia. (1) Meets the diagnostic criteria for insomnia disorder according to ICSD-3 or DSM-5; (2) PSG results: AHI < 5 events/hour (excluding OSA); (3) No other sleep disorders (such as restless legs syndrome, circadian rhythm sleep-wake disorders, etc.); (4) No regular use of hypnotic medications or cognitive behavioral therapy. COMISA group: Meets the diagnostic criteria for both OSA and insomnia.
Exclusion criteria
Exclusion criteria: 1.Presence of severe psychiatric disorders, neurodegenerative diseases, or organic brain lesions; 2.Presence of acute or chronic respiratory, cardiovascular, or endocrine system diseases; 3.History of drug or alcohol dependence; 4.Pregnancy or lactation; 5.Presence of significant structural abnormalities on cranial MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DTI-ALPS index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic Data; | — |
Countries
China
Contacts
Public ContactJiayanlu
The Second Affiliated Hospital Of Zhengzhou University
Outcome results
None listed