Chronic Rhinosinusitis
Conditions
Interventions
Chronic Rhinosinusitis with Nasal Polyps Group:none
Sponsors
School of Public Health(Shenzhen), Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Children aged 6-17 years, adults aged 18-65 years; 2. Meet the clinical diagnostic criteria for chronic rhinosinusitis with nasal polyps (CRSwNP) as stated in the "Chinese Guidelines for the Diagnosis and Treatment of Chronic Rhinosinusitis (2024 Edition)", confirmed by nasal endoscopy and sinus CT examination; 3. Planned to undergo endoscopic minimally invasive or open surgical treatment; 4. Voluntarily participate in this study and sign the informed consent form, and be able to cooperate with sample collection and provide necessary information.
Exclusion criteria
Exclusion criteria: 1. Coexisting other nasal or sinus diseases: including fungal sinusitis, allergic rhinitis, cystic fibrosis, nasal and sinus tumors, etc.; 2. Recent treatment interference: use of antibiotics, oral/systemic corticosteroids, immunotherapy drugs, or anti-allergic medications within 4 weeks before surgery; 3. Coexisting other systemic diseases: including inflammatory diseases, infectious diseases, autoimmune diseases, as well as severe dysfunction of the heart, liver, or kidneys; 4. Special populations: such as pregnant women; 5. Factors affecting sample quality or test results, such as inability to cooperate with preoperative examinations or refusal to provide samples required for research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatty acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| General demographic information;Physical examination;Medical history;Treatment history;Family history;Dietary Habits;Blood Test Report; | — |
Countries
China
Contacts
Public ContactZhen Wang
School of Public Health(Shenzhen), Sun Yat-sen University
Outcome results
None listed