Thoracoscopic surgery
Conditions
Interventions
Etomidate Group (Group E):Anesthesia induction with etomidate
Ciprofol Group (Group C) :Anesthesia induction with ciprofol
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients aged 65 or above. 2. ASA classification is grade I to III. 3. Those who are scheduled to undergo thoracoscopic surgery under general anesthesia (such as lobectomy/segmentectomy, bullae resection, pleural biopsy, etc.) and plan for single-lung ventilation with double-lumen bronchial intubation. 4. The patient or his/her legal representative gives informed consent and signs a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with expected difficult airways (Modified Markov Scale score >= grade III, or with other clear indications of difficult airways). 2. Severe cardiovascular and cerebrovascular diseases: There has been a history of unstable angina pectoris or myocardial infarction within the past six months. NYHA cardiac function classification > or = Grade III, or left ventricular ejection fraction 30 kg/m ² or < 18 kg/m ². 7. The researcher determines that there are other circumstances that make participation in this study unsuitable (such as mental illness, communication disorders, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MAP change value during induction of general anesthesia;HR change value during induction of general anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of vasoactive drugs;Incidence of cardiovascular adverse events;Glucose;Lactic acid; | — |
Countries
China
Contacts
Public ContactJinli Wu
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed