Diseases of hepatobiliary specialty
Conditions
Interventions
A:Dexmedetomidine 0.5 µg/kg was administered
B:Dexmedetomidine 1.0 µg/kg was administered
C:Dexmedetomidine 1.5 µg/kg was administered
D:1 mL of normal saline was administered to each nostril
Sponsors
Tianjin Third Central Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 95 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria were as follows: age >= 65 years; ASA physical status classification I–III; and patients scheduled to undergo ERCP under monitored anesthesia care (MAC).
Exclusion criteria
Exclusion criteria: Exclusion criteria: Patients who lack the capacity to provide informed consent, or are complicated with severe hepatorenal dysfunction, cardiopulmonary insufficiency, or neurocognitive disorders (with Mini-Mental State Examination, MMSE score 180 mmHg, respiratory rate > 25 breaths/min or 120 beats/min or 28 kg/m²; patients with an expected surgical duration exceeding 2 hours; patients judged by the attending physician as unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain assessment: Visual Analogue Scale (VAS) score;Postoperative Quality of Recovery Assessment: QoR-15 Scale;Incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting;Intraoperative dosages of propofol and remifentanil;Number of adverse respiratory and hemodynamic events during surgery; | — |
Countries
China
Contacts
Public ContactHaiyun Wang
Tianjin Third Central Hospital
Outcome results
None listed