Pulmonary Magnetic Resonance Imaging
Conditions
Interventions
Index test:Phase-Resolved Functional Lung (PREFUL) MRI
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Subject eligibility will be met if one of the following criteria is fulfilled: For Healthy Volunteers: (1) Age >= 18 years; (2) In good health with no history of cardiovascular or pulmonary diseases; (3)Non-smoker or smoking history of less than 1 pack-year; (4)No upper respiratory tract infection within the past 4 weeks. For Patients with Respiratory System Diseases: (1) Age >=18 years; (2) Diagnosis of a respiratory system disease, such as pneumonia, pulmonary tuberculosis, asthma, chronic obstructive pulmonary disease, bronchiectasis, pulmonary embolism, pulmonary fibrosis, lung cancer, etc.
Exclusion criteria
Exclusion criteria: 1.For Healthy Volunteers: (1) Contraindications to magnetic resonance imaging (e.g., presence of metallic implants, claustrophobia, pregnancy); (2)Smoking on the day of the examination; (3)Contraindications to conventional pulmonary function tests (e.g., history of temporomandibular joint dislocation, having undergone endoscopy and biopsy on the same day, poor cooperation, or physically debilitated patients). 2.For Patients with Respiratory System Diseases: Contraindications to magnetic resonance imaging (e.g., presence of metallic implants, claustrophobia, pregnancy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ventilation defect percentage;Flow-volume loop correlation coefficient;Perfusion defect percentage;Perfusion quantified; | — |
Secondary
| Measure | Time frame |
|---|---|
| Regional ventilation;Ventilation/perfusion matching-related indices; | — |
Countries
China
Contacts
Public ContactChunchao Xia
West China Hospital, Sichuan University
Outcome results
None listed