Prostate Cancer
Conditions
Interventions
Experimental group:In addition to targeted biopsy combined with systematic biopsy, perilesional biopsy is performed around the index lesion.
Control group:None
Sponsors
Northern Jiangsu People's Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Serum prostate-specific antigen (PSA) level > 4 ng/mL; 2. Prostate lesion with a Prostate Imaging Reporting and Data System (PI-RADS) version 2.1 score of =4, or a clearly suspicious lesion assigned a PI-RADS score of 3 on multiparametric MRI; 3. Patient scheduled to undergo or has undergone prostate biopsy;
Exclusion criteria
Exclusion criteria: 1. Contraindications to prostate biopsy; 2. Prior history of prostate biopsy; 3. Previous treatment with androgen deprivation therapy (ADT) or pelvic radiotherapy; 4. History of transurethral resection of the prostate (TURP).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| csPCa rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive rate;The rates of pathological up-regulation and down-regulation after radical treatment; | — |
Countries
China
Contacts
Public ContactXuefei Ding
Northern Jiangsu People's Hospital
Outcome results
None listed