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The effectiveness and cost-effectiveness of mechanical prophylaxis for reducing venous thromboembolism after transurethral resection of the prostate: A single-center retrospective cohort study

The effectiveness and cost-effectiveness of mechanical prophylaxis for reducing venous thromboembolism after transurethral resection of the prostate: A single-center retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116500
Enrollment
Unknown
Registered
2026-01-12
Start date
2026-01-15
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Venous thromboembolism

Interventions

Group without mechanical prophylaxis:None
Group with mechanical prophylaxis:None

Sponsors

Xiangya Hospital Central South University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Admitted to the urology department of our hospital from January 1, 2017 to June 30, 2025. 2. Age >= 18 years old. 3. The main diagnosis is benign prostatic hyperplasia. 4. Underwent transurethral resection of the prostate.

Exclusion criteria

Exclusion criteria: 1. Preoperatively diagnosed with VTE (deep vein thrombosis or pulmonary embolism). 2. Undergoing surgery due to malignant tumors such as prostate cancer. 3. Requiring long-term therapeutic anticoagulation during the perioperative period for other indications (such as atrial fibrillation, post-mechanical valve surgery, etc.). 4. Severe deficiency of medical records, making it impossible to obtain key variables (such as preventive measures, outcome events, etc.). 5. Postoperative hospital stay significantly prolonged (> 14 days) due to non-VTE reasons (such as severe bleeding, cardiovascular and cerebrovascular accidents), as their VTE risk is not comparable to that of regular patients.

Design outcomes

Primary

MeasureTime frame
The incidence of symptomatic venous thromboembolism within 90 days after surgery;The incidence of clinically significant major bleeding events during the postoperative hospital stay and within 30 days;

Secondary

MeasureTime frame
The incidence of any bleeding event;Postoperative blood transfusion rate;Postoperative hospital stay;VTE-related readmission rate;Incremental cost-effectiveness ratio;

Countries

China

Contacts

Public ContactWang Zhao

Xiangya Hospital Central South University

wangzhaoxy@csu.edu.cn+86 151 1635 8241

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026