Lcerative colitis
Conditions
Interventions
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age: Age >=18 years old, <=80 years old. (2) Diagnosis: Individuals with clinically active UC manifestations and those previously diagnosed with UC who are currently in remission. (3) Complete baseline clinical data: Laboratory tests such as CRP, erythrocyte sedimentation rate, and calprotectin are available; Be able to describe in detail the disease process, medication history, complications (such as intestinal obstruction, fistula), etc. (4) Pathological evidence: Those who can be examined in conjunction with colonoscopy and ultrasound colonoscopy and undergo tissue sample testing. (5) Informed consent: Willing to sign the informed consent form and recognize the purpose and process of participating in this study.
Exclusion criteria
Exclusion criteria: (1) Complicated with severe diseases: There are serious cardiovascular diseases, liver diseases, kidney diseases and other comorbidities that affect the study. (2) Recent surgery: Patients who have undergone other major surgeries in the recent period (<=6 months). (3) And other intestinal diseases: such as intestinal tumors, polyps, and diverticulitis other than colon cancer. (4) Mental illness: Patients with a severe history of mental illness or cognitive impairment that affects their understanding and participation in the research. (5) Pregnant or lactating women: Women who are pregnant or lactating during the study period.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Clinical remission rate;Biochemical remission rate;Surgery rate;All-cause mortality;EUS-related adverse event rate; | — |
Primary
| Measure | Time frame |
|---|---|
| Transmural healing rate;Histologic healing rate;Mucosal healing rate; | — |
Countries
China
Contacts
Public ContactQu Bo
The Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed