Chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 40-80 years old, with Shanghai registration, permanent residents of Jiangchuan Road, Zhuanqiao Town and Maqiao Town in Minhang District. 2.It meets the diagnostic criteria for stable COPD in the Diagnosis and Treatment Guidelines for Chronic Obstructive Pulmonary Disease (Revised 2021). 3.Patients are willing to participate in the study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients who are currently in an acute exacerbation or are at high risk of acute exacerbation during a stable period; 2.Patients who are unable to cooperate with lung function tests or have contraindications in lung function tests; 3.Patients with severe mental illness or cognitive impairment; 4.Patients with severe cardiovascular and cerebrovascular diseases; 5.Patients who are pregnant, participate in other clinical trial interventions, or have special circumstances such as limited activities; 6.Patients who are already receiving specific treatment or have other major health problems; 7.Patients had received other treatments or interventions in the past that could have affected the study results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of acute exacerbations during the intervention period; | — |
Secondary
| Measure | Time frame |
|---|---|
| C-reactive Protein;Forced Expiratory Volume in One Second / Forced Vital Capacity;Forced Expiratory Volume in One Second;Peak Expiratory Flow;modified Medical Research Council Dyspnea Scale Score;Toll-like Receptor 4;Tumor Necrosis Factor-a;Interleukin-33;St. George's Respiratory Questionnaire Score;COPD Assessment Test Score;Annual average number of hospitalizations / costs; | — |
Countries
China
Contacts
Shanghai Fifth Peoople's Hospital