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Comparison of the Effects of Inferior Vena Cava and Internal Jugular Vein Ultrasound-Guided Fluid Therapy on Hemodynamics and Prognosis in Elderly Patients Undergoing Femoral Surgery during General Anesthesia Induction

Comparison of the Effects of Inferior Vena Cava and Internal Jugular Vein Ultrasound-Guided Fluid Therapy on Hemodynamics and Prognosis in Elderly Patients Undergoing Femoral Surgery during General Anesthesia Induction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116475
Enrollment
Unknown
Registered
2026-01-11
Start date
2026-01-11
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-induction hypotension

Interventions

Experimental Group 1(IVC-CI):Group guided by inferior vena cava ultrasound (IVC-CI) for fluid resuscitation: Measure the patients inferior vena cava collapse index (IVC-CI) before surgery and group as
2. If IJV-CI < 40%, administer fluids at a rate of 4ml/kg·h before induction, and begin anesthesia induction after 10 minutes
control group(Traditional fluid replacement):Preoperatively, no ultrasound measurements or fluid resuscitation interventions are performed. According to the 421 rule, physiological needs and intraoper

Sponsors

The First Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients scheduled to undergo elective total hip replacement surgery and femoral fracture reduction and internal fixation under general anesthesia at Dalian Medical University Affiliated First Hospital from October 2025 to October 2026; 2. Age >= 65 years; 3. ASA classification II-III; 4. Voluntarily sign an informed consent form;

Exclusion criteria

Exclusion criteria: 1. Anaphylactic shock;2. Patients predicted to have difficult airways, re-intubation, or prolonged intubation [defined as intubation time greater than 30 seconds]; 3. Overinflated lungs, such as in patients with asthma, respiratory distress syndrome, or chest deformities; 4. Chronic heart failure patients with LVEF 180/110 mmHg, with an interval of 1 minute;(7) inconsistent measurements of the same indicator at baseline (i.e., a difference of >0.2 cm between any two respiratory cycles out of three);(8) poor iliac fascia block effect (needling the front and lateral side of the thigh, with the patient reporting significant pain sensation).

Design outcomes

Primary

MeasureTime frame
Blood pressure;Trans-thoracic echocardiographic indicators;

Secondary

MeasureTime frame
Blood gas analysis;Myocardial markers;Lung ultrasound B-lines;

Countries

China

Contacts

Public ContactLv Meihong

The First Affiliated Hospital of Dalian Medical University

1797261510@qq.com+86 180 9887 6206

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026