Chronic Ankle Instability
Conditions
Interventions
Healthy control group:Sham stimulation (no actual electrical stimulation)
tDCS group:Multichannel targeted transcranial direct current stimulation (tDCS), parameters: 2 mA for 20 minutes, targeting established hypoactive cortical regions.
NMES group:Multichannel targeted neuromuscular electrical stimulation (NMES), stimulating targeted muscle groups with intensity controlled within safe thresholds.
Combined group (tDCS + NMES):Simultaneous combined stimulation with tDCS and NMES, using parameters identical to those in their respective single-group protocols.
Sponsors
Wuhan Sports University
Eligibility
Sex/Gender
Male
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. History of at least one moderate to severe lateral ankle sprain with associated inflammatory symptoms (i.e., pain, swelling, discoloration) resulting in interruption of training or competition for more than 3 days; 2. Two ankle sprains within the 3–6 months prior to the study; 3. Persistent sensation of "instability" or "giving way" in the injured ankle during daily activities, with a Functional Ankle Instability Questionnaire (Id FAI) score >=11 and a Cumberland Ankle Instability Tool (CAIT) score <=24; 4. Right-dominant leg, with the injured leg being the right leg.
Exclusion criteria
Exclusion criteria: 1. History of lower limb surgery or fracture; 2. Ankle sprain occurring shortly before the study initiation; 3. History of conditions severely impairing cognitive function, such as concussion or learning disabilities; 4. History of balance or vestibular disorders; 5. Positive talus tilt test and anterior drawer test; 6. Currently taking medications that may affect cognitive function, such as anesthetics, antidepressants, or anxiolytics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective outcome measures: CAIT (Cumberland Ankle Instability Tool); VAS (Visual Analog Scale for pain); Activities of Daily Living Disability Questionnaire.;Electromyographic (EMG) parameters: Reaction time of key muscle groups; Peak activation level; Muscle synergy index.;Kinematic and kinetic parameters: Single-leg landing center stability; Lower limb joint angles; Ground contact duration during landing; Ground reaction force metrics.; | — |
Countries
China
Contacts
Public ContactWei Mengli
Wuhan Sports University
Outcome results
None listed