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Perioperative Safety Evaluation of a Remimazolam Besylate Induction-Maintenance General Anesthesia Regimen :A Multicenter,Real-World Study on the Incidence of Intraoperative Awareness

Perioperative Safety Evaluation of a Remimazolam Besylate Induction-Maintenance General Anesthesia Regimen :A Multicenter,Real-World Study on the Incidence of Intraoperative Awareness

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116450
Enrollment
Unknown
Registered
2026-01-09
Start date
2026-01-15
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Awareness with recall

Interventions

Observational group:None

Sponsors

Deyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The age shall be >= 18 years old and <= 80 years old; 2. No restriction on gender; 3. The patient or their legal representative shall sign a written informed consent form.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women (with a positive urine pregnancy test); 2.Patients with a history of allergy to remimazolam or opioid drugs (e.g., remifentanil); 3.Patients with myasthenia gravis, muscular dystrophy, or other diseases that affect neuromuscular transmission; 4.Patients with a history of mental illness (e.g., schizophrenia, bipolar disorder); 5.Patients with severe organ dysfunction: hepatic insufficiency (Child-Pugh Class C); renal insufficiency (eGFR < 30 mL/min/1.73m^2); uncontrolled heart failure (NYHA Class ?–?); 6.Other contraindications: patients judged by the investigator to be at high risk for general anesthesia or otherwise unsuitable for participation in the study.

Design outcomes

Primary

MeasureTime frame
The incidence of intraoperative awareness in patients undergoing general anesthesia induction-maintenance with remimazolam;

Secondary

MeasureTime frame
The incidence and severity of postoperative nausea and vomiting in patients undergoing general anesthesia induction-maintenance with remimazolam;

Countries

China

Contacts

Public ContactZhang Xianjie

Deyang People's Hospital

zxianjiemazui@163.com+86 139 8108 8319

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026