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The Effectiveness and Mechanisms of Novel Graded Motor Imagery Therapy in Improving Upper Limb Function in Stroke Patients

The Effectiveness and Mechanisms of Novel Graded Motor Imagery Therapy in Improving Upper Limb Function in Stroke Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116426
Enrollment
Unknown
Registered
2026-01-09
Start date
2026-01-16
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Conventional Rehabilitation Training Group:In addition to the 30-minute conventional training, active activities were incorporated. The content of these active activities was consistent with that of c
Standard Graded Motor Imagery Group:The intervention consisted of the 30-minute conventional training supplemented with an additional 30 minutes of Standard Graded Motor Imagery training, administered
reaction time = 2.0±0.5 seconds). If these criteria were not met within six sessions, two additional discrimination sessions were provided. Regardless of performance, motor imagery was gradually intro

Sponsors

School of Rehabilitation Medicine, Shandong Second Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of the Chinese Classification of Cerebrovascular Diseases (2019), with a confirmed first-time ischemic or hemorrhagic stroke by cranial computed tomography (CT) or magnetic resonance imaging (MRI); (2) Present with unilateral upper limb hemiplegia, with a disease course of 2 weeks to 6 months, and stable vital signs; (3) Aged between 35 and 75 years; (4) Brunnstrom Stage of the upper limb is III-V, and Brunnstrom Stage of the hand is II-V; (5) Achieve Sitting Balance Grade III and able to maintain a sitting position for 30 minutes; (6) Exhibit no significant cognitive impairment (Mini-Mental State Examination score >=17 for illiterate individuals, >=20 for those with primary school education, >=24 for those with secondary education or above); (7) Possess sufficient motor imagery ability (i.e., a score higher than 25 on the short-form Kinesthetic and Visual Imagery Questionnaire); (8) Provide written informed consent.

Exclusion criteria

Exclusion criteria: (1) History of organic brain diseases; (2) Severe impairment of visceral organ function; (3) Comorbid sensory dysfunctions, such as visual, auditory, or speech disorders; (4) Severe upper limb spasticity (Modified Ashworth Scale score > 3) or pain (Visual Analogue Scale score indicating severe pain), or other major medical conditions/comorbidities that affect upper limb use or cause significant pain; (5) Presence of psychiatric or psychological disorders, including depression, anxiety disorders, or bipolar disorder; (6) Recent participation in similar rehabilitation training programs.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment of Upper Extremity ;

Secondary

MeasureTime frame
Modified Ashworth Scale;Box and Block Test;Modified Barthel Index;Canadian Occupational Performance Measure;functional Near-Infrared Spectroscopy Data Acquisition;

Countries

China

Contacts

Public ContactLi Kuicheng

School of Rehabilitation Medicine, Shandong Second Medical University

13926144818@163.com+86 536 864 2089

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026