Adenoid hypertrophy, Tonsil hypertrophy
Conditions
Interventions
Group P:In group P, penehyclidine hydrochloride was diluted into 0.1mg/ml, dispensed in a 10ml syringe, and the anesthesiologist administered 0.2ml/kg (i.e., penehyclidine hydrochloride 0.02mg/kg).
Group C:Group C was given 10ml normal saline, and 0.2ml/kg normal saline was given by the anaesthetist
Sponsors
Zhongda Hospital Southeast University
Eligibility
Sex/Gender
All
Age
No minimum to 12 Years
Inclusion criteria
Inclusion criteria: (1) ASA is classified as Grade I to III. (2) Age 0-12 years old; (3) It is planned to perform elective general anesthesia tonsillectomy and/or adenoidectomy.
Exclusion criteria
Exclusion criteria: (1) Congenital diseases or abnormal liver and kidney functions; (2) Chronic lung diseases (cystic fibrosis of the lung, bronchial dysplasia, pulmonary hypertension, etc.); (3) There was a severe upper respiratory tract infection before the operation; (4) Neuromuscular diseases, cerebral palsy, epilepsy; (5) Intubation has been performed or tracheotomy has been carried out; (6) Those who plan to be admitted to the ICU after the operation; (7) Glaucoma patients; (8) Family members or guardians refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative respiratory adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| The timing (induction period, postoperative recovery period) and degree of respiratory adverse events;Heart rate;Acetylcholinesterase, interleukin-6 (IL-6) and interleukin-8 (IL-8);Real-time heart rate variability;Pain score (wong-baker score);Restlessness delirium score (PAED score); | — |
Countries
CHINA
Contacts
Public ContactSun Jie
Zhongda Hospital Southeast University
Outcome results
None listed