Pain
Conditions
Interventions
tDCS treatment group:A 3-day M1-tDCS intervention, with 20 minutes per day. Stimulation pattern: anodal tDCS with target over the M1 and a current intensity of 1mA.
tRNS treatment group:A 3-day intervention targeting the M1, with 20 minutes per day. Stimulation pattern: tRNS+DC-offset, with target over the M1 and a current intensity of 1mA.
Sham group:A 3-day sham intervention, with 20 minutes per day. Stimulation pattern: sham stimulation, with target over the M1 and a current intensity of 1mA.
Sponsors
School of Psychology, Shenzhen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-65 years, regardless of gender; 2.No history of epilepsy, neurological disorders, acute or chronic pain conditions, claustrophobia, or contraindications to transcranial magnetic stimulation (TMS); 3.Participants must provide written informed consent and agree to participate in this study; 4.Have not undergone any physical therapy treatments, such as repeated transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), or transcranial alternating current stimulation (tACS) within the past 1 months.
Exclusion criteria
Exclusion criteria: 1.Psychiatric disorders (bipolar disorder, depression, etc.), neurological disorders (epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease, motor neuron disease), history of brain surgery or tumors, heart disease, rheumatic/inflammatory diseases (e.g., rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, Sjögren's syndrome); 2.Metal on or inside the body; 3.Pregnancy; 4.History of drug or other substance dependence; 5.Use of analgesic-related medications within the last 3 days;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity;Pain unpleasantness;Pain sensitivity trait;Conditioned pain modulation;Temporal summation of pain;TMS-induced brain response;EEG resting-state brain activity;fMRI resting-state brain activity; | — |
Countries
China
Contacts
Public ContactWeiwei Peng
School of Psychology, Shenzhen University
Outcome results
None listed