Thyroid
Conditions
Interventions
Gold Standard:In the clinical diagnosis and differential diagnosis of thyroid nodules, histopathological examination after surgical resection is regarded as the ultimate gold standard.
Index test:SR CEUS parameters of thyroid nodules (microvessel density, flow velocity, flow direction) + shear wave viscoelastic imaging parameters (elastic modulus, viscous coefficient)
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Ultrasound diagnosis of patients with thyroid space-occupying lesions; (2) Patients who are expected to obtain FNA or surgical pathological results; (3) The patient's age is >=18 years old and =75%); (7) Only one nodule is selected for each patient (if there are multiple nodules expected to be benign, the one with the largest diameter is selected; if there are multiple nodules with different malignant possibilities, the one with the highest malignant possibility is selected; if there are multiple nodules with the same malignant possibility, one of them is randomly selected).
Exclusion criteria
Exclusion criteria: (1) Patients whose nodules have undergone surgical treatment or who have a history of radiation exposure to the head and neck; (2) Patients with abnormal test results of T3, T4 and TSH; (3) Patients with thyroid nodules with a maximum diameter of less than 1 cm or more than 4.0cm; (4) Patients with fluid parts of thyroid nodules greater than 25%; (5) Those without definite pathological results (Bethesda I/III/IV patients who have not undergone surgery are excluded from the group).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy;Sensitivity;Specificity;The area under the receiver operating characteristic curve;Precision rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| False Positive Rate;False Negative Rate;F1 Score; | — |
Countries
China
Contacts
Public ContactZhang Yifeng
Shanghai General Hospital
Outcome results
None listed