Helicobacter pylori infection
Conditions
Interventions
Amoxicillin-resistant group:None
The group that is not resistant to amoxicillin:None
Sponsors
Huzhou Center Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged between 16 and 80 years; 2. Patients who have lived in the local area for a long time (residence time >=5 years); 3. Patients with stable conditions and no severe systemic diseases; 4. Complete clinical data; 5. Patients who have given informed consent and signed the relevant consent forms for endoscopy, HP culture, and drug susceptibility testing; 6. At least one positive result on the 13C-urea breath test.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to gastroscopy or those who have difficulty cooperating with the procedure; 2. Patients who have previously undergone gastrointestinal surgery or have gastrointestinal malignancies; 3. Patients with gastrointestinal bleeding, gastrointestinal ulcer perforation, or pyloric obstruction; 4. Patients who have taken antibiotics, bismuth agents, traditional Chinese medicine, proton pump inhibitors, H2 receptor antagonists, P-CABs, or other drugs that may affect test results within the past month; 5. Patients with severe underlying conditions such as heart, lung, liver, or kidney dysfunction, or severe psychiatric disorders; 6. Pregnant or breastfeeding women; 7. Drug allergies: patients allergic to study medications including penicillin, PPIs, furazolidone, or potassium bismuth citrate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eradication rate;Minimal Inhibit Concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ampicillin resistance gene detection;The change in amoxicillin resistance rate; | — |
Countries
China
Contacts
Public ContactJiang Liu
Huzhou Center Hospital
Outcome results
None listed