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Effect of high flow oxygenation via nasopharyngeal airway on incidence of hypoxia during sedated bronchoscopy in patients with obesity: A randomised controlled trial

Effect of high flow oxygenation via nasopharyngeal airway on incidence of hypoxia during sedated bronchoscopy in patients with obesity: A randomised controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116346
Enrollment
Unknown
Registered
2026-01-08
Start date
2026-01-12
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyoxemia

Interventions

Traditional nasal cannula oxygen therapy group(C group):Oxygen is administered through a nasal cannula at a flow rate of 2 l/min, If necessary, the flow rate can be increased to 6 l/min.
High flow oxygenation via nasopharyngeal airway group(H group):Close one of the soft cavities of the high-flow dual-chamber nasal catheter with tape, and connect the other soft cavity to the nasophary

Sponsors

Shandong Provincial Public Health Clinical Center (Shandong University Affiliated Public Health Clinical Center)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for sedated bronchoscopy treatment; 2. BMI >= 28; 3. 18 <= Age <= 70 years old; 4. Patients are informed of this study and have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Coagulation disorders or a tendency to nosebleeds; 2. Previous history of nasopharyngeal surgery, nasal deformity, nasal tissue hyperplasia, etc.; 3. Respiratory failure or circulatory failure; 4. Acute myocardial infarction within the last 6 months; 5. Need for long-term oxygen therapy or home mechanical ventilation; 6. Oral, nasal or throat infections; 7. Pregnancy; 8. Intracranial hypertension, cranial base defect or fracture; 9. Tracheotomy status; 10. Need for endotracheal intubation or laryngeal mask ventilation; 11. Severe liver and kidney dysfunction.

Design outcomes

Primary

MeasureTime frame
hypomexia(75%<=SpO2<90% ,<=60s);

Secondary

MeasureTime frame
The incidence of subclinical respiratory depression (90% 60 seconds);Minimun Spo2;The required airway intervention methods and the number of times needed;

Countries

China

Contacts

Public ContactYanwu Jin

Shandong University Affiliated Public Health Clinical Center

jinyanwu_aa@163.com+86 176 6008 5535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026