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Clinical Study on Precision Fluid Resuscitation Driven by Multimodal Monitoring to Improve Microcirculation and Prognosis in Patients with Septic Shock

Clinical Study on Precision Fluid Resuscitation Driven by Multimodal Monitoring to Improve Microcirculation and Prognosis in Patients with Septic Shock

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600116344
Enrollment
Unknown
Registered
2026-01-08
Start date
2026-01-08
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Modal monitoring guided liquid therapy group (exposure group):On the basis of continuous traditional vital sign monitoring (blood pressure, heart rate, blood oxygen, urine output, etc.), additional an
Traditional liquid therapy group (non exposure group):During the same period, only traditional liquid therapy guided by routine clinical assessments, vital signs (blood pressure, heart rate, urine out

Sponsors

Linyi Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to No maximum

Inclusion criteria

Inclusion criteria: Two ICU doctors from our intensive care unit jointly screened patients who 1. meet the diagnostic criteria for septic shock in the guidelines for the diagnosis and treatment of sepsis and septic shock; 2. Age: >= 18 years old; Regardless of the patient's awareness, cooperation in the examination, 3. and willingness of the patient or guardian to participate in this study and sign a written informed consent form, they can be included.

Exclusion criteria

Exclusion criteria: 1 There are absolute contraindications to using multimodal monitoring; 2 Late stage patients with malignant tumors; 3 The patient is in an endangered state and is expected to die within 72 hours; 4 Patients with incomplete clinical data; 5 Pregnant and lactating women; 6 Participants who have participated in other clinical intervention trials within 30 days.

Design outcomes

Primary

MeasureTime frame
CRT;

Countries

China

Contacts

Public Contactkonglingchen

Linyi Central Hospital

klch0313@163.com+86 151 0669 1551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026