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Influencing factors, predictive model and prognostic impact of pathological upgrading in patients with prostate cancer with Gleason score 3+3 undergoing radical prostatectomy: A multicenter study based on the Chinese population

Influencing factors, predictive model and prognostic impact of pathological upgrading in patients with prostate cancer with Gleason score 3+3 undergoing radical prostatectomy: A multicenter study based on the Chinese population

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116333
Enrollment
Unknown
Registered
2026-01-08
Start date
2026-01-31
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate Cancer

Interventions

Case series:NA

Sponsors

Northern Jiangsu People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Patients diagnosed with prostate cancer by prostate biopsy , with a Gleason score of 3+3, who underwent radical prostatectomy; and were clinically diagnosed with localized prostate cancer.

Exclusion criteria

Exclusion criteria: Patients with other malignant tumors before prostate biopsy; patients who have taken 5a-reductase inhibitors orally for more than 3 months before biopsy; patients with incomplete data.

Design outcomes

Primary

MeasureTime frame
BCR-free survival;—

Secondary

MeasureTime frame
Time to first subsequent therapy;—

Countries

China

Contacts

Public ContactXuefei Ding

Northern Jiangsu People's Hospital

xuefeid@126.com+86 180 5106 1234

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026