Anxiety
Conditions
Interventions
Placebo control group:Normal diet and routine training plus 150 mL of water per day
Intervention group (creatine supplementation):Normal diet and routine training plus 3 g of creatine dissolved in 150 mL of water per day
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
11 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for Participants in the Current Status Survey(Participants meeting all of the following criteria were included): (1)Adolescent athletes currently enrolled at the Shanghai Sports School, with no restrictions on gender, grade level, or sport, aged 11–18 years; (2)Participants who provided written informed consent. 2. Inclusion Criteria for Participants in the Randomized Controlled Trial: (1)Adolescent athletes currently enrolled at the Shanghai Sports School, with no restrictions on sex, grade level, or sport, aged 11–18 years; (2)A score of 45 or higher on the Self-Rating Anxiety Scale (SAS); (3)At least one year of regular sports training experience, with a training frequency of at least 3–4 sessions per week; (4)No history of cardiovascular disease, diabetes, hepatic or renal insufficiency, or other health conditions that may affect exercise performance; (5)No history of sports-related injuries, particularly injuries involving body regions relevant to the sport participated in, such as the shoulder, knee, or spine; (6)No use of creatine or other performance-enhancing supplements within three months prior to the start of the trial; (7)Relatively stable and regular dietary habits, with no engagement in extreme weight-loss diets or very high-protein diets; (8)Provision of written informed consent.
Exclusion criteria
Exclusion criteria: 1. Exclusion Criteria for Participants in the Current Status Survey(Participants meeting any of the following criteria were excluded): (1)Failure to provide written informed consent; (2)Unwillingness or inability to continue participation in the survey, or withdrawal of informed consent; (3)Discovery after enrollment that the participant did not meet the inclusion criteria or met any exclusion criteria; (4)Determination by the investigators that continued participation would be detrimental to the participant; (5)Termination of the survey by the investigators. 2. Exclusion Criteria for Participants in the Randomized Controlled Trial: (1)Presence of any known chronic diseases, such as diabetes mellitus, cardiovascular disease, or chronic kidney disease, that may affect athletic performance or metabolism; (2)A history of severe sports-related injuries, such as fractures or surgical history involving the knee, shoulder, or spine; (3)Use of creatine or other performance-enhancing supplements within three months prior to the start of the trial; (4)Engagement in strict dieting or adherence to a very low-calorie diet; (5)Adherence to extreme vegetarian diets or other special dietary patterns; (6)Recent participation in extreme training programs or major changes in training regimen; (7)Presence of cognitive impairment or psychiatric disorders that may limit the participant’s ability to understand the study requirements or comply with study procedures; (8)Failure to provide written informed consent; (9)Unwillingness or inability to continue participation in the trial, or withdrawal of informed consent; (10)Discovery after enrollment that the participant did not meet the inclusion criteria or met any exclusion criteria; (11)Determination by the investigators that continued participation would be detrimental to the participant; (12)Termination of the study by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety rating scale (Self-Rating Anxiety Scale, SAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety rating scale(Screen for Child Anxiety Related Emotional Disorders, SCARED);Anxiety rating scale(State–Trait Anxiety Inventory, STAI);Sleep quality scale(Pittsburgh Sleep Quality Index, PSQI);Handgrip strength (kg);Body weight (kg);Skeletal muscle mass (kg);Fat mass (kg);Waist-to-hip ratio;Erythrocyte creatine (µmol/g Hb); | — |
Countries
China
Contacts
Public ContactShao Chunhai
Huashan Hospital, Fudan University
Outcome results
None listed