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Discovery and Validation of Novel Early-Warning Biomarkers for Acute Pancreatitis Based on Metabolic Regulation

Discovery and Validation of Novel Early-Warning Biomarkers for Acute Pancreatitis Based on Metabolic Regulation

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600116329
Enrollment
Unknown
Registered
2026-01-08
Start date
2026-01-17
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute pancreatitis

Interventions

Sponsors

The First Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.[Normal population (control group)] Aged 18-80 years, matched with the age of the patient population; healthy volunteers for outpatient physical examination (no recent antibiotic use, no autoimmune system diseases). 2.[Patient population (study group)]: Patients aged between 18 and 80 years with acute pancreatitis who meet the diagnostic criteria of the Atlanta criteria for acute pancreatitis; with good compliance, patients or their families are able to understand the study protocol and are willing to participate in this study, and maintain their current lifestyle during the study period, providing written informed consent; with complete medical records and regular follow-ups.

Exclusion criteria

Exclusion criteria: 1.Patients with chronic pancreatitis or pancreatic cancer; 2.Lost to follow-up; 3.Patients with severe organic diseases, such as malignant tumors, acute myocardial infarction, or large-area cerebral infarction; 4.Pregnant or lactating women; 5.Failure to provide signed informed consent.

Design outcomes

Primary

MeasureTime frame
Lipid and lipoprotei related metabolites;

Secondary

MeasureTime frame
Serum bile acid assay;Gut microbiota abundance analysis;

Countries

China

Contacts

Public ContactShang Dong

The First Affiliated Hospital of Dalian Medical University

shangdongdalian@163.com+86 411 83635963

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026