Obesity/overweight
Conditions
Interventions
DHA algal oil group:DHA algae oil, take once daily with meals
C15:0 DHA algal oil group:C15:0 DHA algal oil, take once daily with meals
Placebo group:Placebo, once daily, taken with food
Sponsors
Xiamen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age: Children aged 12-15 years, any gender; 2. According to the World Health Organization's child growth standards, children are considered obese if their body mass index (BMI) exceeds 2 standard deviations above the mean BMI for children of the same age and sex, i.e., a BMI equal to or greater than the obesity threshold for the corresponding age and sex group; 3. Parents (or legal guardians) are willing to provide basic demographic information and complete the required surveys; 4. If the child has previously used related algal oil or fish oil products, they must have discontinued use for at least 4 weeks; 5. The child and their guardian understand the experimental procedures and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with severe liver and kidney dysfunction, cardiovascular diseases, endocrine disorders (such as thyroid dysfunction), or other diseases affecting lipid metabolism or intestinal function; 2. Individuals who have used antibiotics, probiotics, or other drugs that may affect gut microbiota within the past 3 months; 3. Individuals allergic to algae; 4. Individuals who have recently had significant changes in diet or are participating in other weight loss programs; 5. Any other conditions that the researcher believes may hinder compliance or interfere with the completion of the study; 6. Subjects whom the researcher believes cannot or is unwilling to follow the protocol or have any other condition that may hinder compliance or interfere with the completion of the study; 7. Subjects currently participating in clinical trials or who have received study drugs within 180 days after screening; 8. Subjects currently using other algal oil or fish oil products; 9. Subjects who have not given informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition ;Blood lipidomics;BMI-z;lipid profiles;blood glucose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Basic information on demography;Mental Health Questionnaire;Questionnaires on exercise, satiety, gastrointestinal symptoms, faecal pattern and frequency of bowel movements.;Blood biochemistry and immune markers;Gut Microbiota;conitive function;SCFAs; | — |
Countries
China
Contacts
Public ContactChenxi Cai
School of Public Health, Xiamen University
Outcome results
None listed