Diabetic foot
Conditions
Interventions
Experimental group:Experimental group: After conventional surgical debridement, the wound was rinsed with hydrogen nanobubble water (once daily, with the same rinsing time and amount as the control gr
Control group:Control group: After routine surgical debridement, the wound was rinsed with 0.9% saline (once daily), followed by covering with a sterile dressing.
Sponsors
The Second Affiliated Hospital of Shandong First Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the WHO diagnostic criteria for diabetes and are confirmed to have diabetic foot ulcers; 2. Patients with Wagner grade 2-4; 3. Aged 18-80, conscious, and able to cooperate with treatment and follow-up; 4. Willing to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, liver, or kidney failure, or malignant tumors; 2. Those who have recently used immunosuppressants or glucocorticoids; 3. Patients requiring amputation due to extensive limb necrosis; 4. Pregnant or breastfeeding women; 5. Individuals with poor compliance or who withdraw from the trial midway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing rate;VAS Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound oxidative stress levels;Serum inflammatory markers; | — |
Countries
China
Contacts
Public ContactDing Xiaolin
The Second Affiliated Hospital of Shandong First Medical University, Tai'an, Shandong Province
Outcome results
None listed