Hypotension after general anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >=65 years old, it is proposed to perform elective total anesthesia surgery, and the operation time is expected to exceed 1 hour; 2. American Association of Anesthesiologists (ASA) Grade I-III; 3.The patient or his/her family sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. There is a serious heart valve disease and cardiomyopathy affecting cardiac hemodynamics; 2. There is Inferior vena cava malformation, thrombosis or local lesions interfere with ultrasound imaging observation; 3. The terminal stage of liver and kidney failure, Short life expectancy; 4. Unable to cooperate with the completion of ultrasound examination and related monitoring processes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The area under the ROC curve, sensitivity, and specificity of IVC-CI for predicting hypotension within 24 hours postoperatively.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative: ASA classification, white blood cell count, platelet count, hemoglobin, albumin, creatinine clearance;Intraoperative: surgical approach, surgical site, operative time, intraoperative crystalloid and colloid infusion volume, intraoperative blood loss and transfusion volume, intraoperative urine output, intraoperative propofol and remifentanil usage;Postoperative: incidence of hypotension within 24 hours, use of opioid analgesics, total opioid dosage, intra-24h crystalloid and colloid infusion volume, blood transfusion volume, drainage volume, urine output, time to resumption of oral intake, assessment of new postoperative complications: (postoperative pulmonary edema, pulmonary infection, gastrointestinal reactions, delayed wound healing, acute kidney injury, cardiovascular and cerebrovascular events [including heart failure, cerebral infa; | — |
Countries
China
Contacts
Affiliated Hospital of Yan'an University